Word: nucleic
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...coatless inner part of the virus is essentially a molecule of nucleic acid, but inside the factory it behaves like an immensely efficient agent taking over a captured industry. It seems to know where the production schedules and blueprints are-and it throws them away. In their place, it issues orders for the production of nothing but hundreds or thousands of copies of itself, plus an equal number of protein coats to fit. The cell-factory rushes to fill the massive order. It becomes strewn with waste materials. The strain tells. About the time the cell fills the invader...
...wrong genetic information,' perhaps through the entry of a virus into the cell. The virus need not necessarily multiply within the cell; all that is necessary is for a piece of the virus' RNA or DNA to be substituted for part of the cell's normal nucleic acid...
...cases, said Dr. Huppert. it will incorporate the "foreign" information and reproduce abnormally, starting a cancer. The likelihood of this is increased when an other, non-cancer-causing virus happens to be present. Dr. Huppert said he and his colleagues have induced tumors in animals with the nucleic-acid "core'' of a virus found in a human tumor...
...recently been shown to be associated with a supernumerary chromosome: victims have 47 instead of the normal 46. Some cases of intersex abnormalities have one or even two extra female (X) chromosomes. Within the chromosomes, a defective gene may fail in its function because a single fraction of its nucleic acid molecule is aberrant and inutile. The time may come, suggested the Rockefeller Institute's Geneticist Edward L. Tatum, when medical men will be able to replace a defective gene with a specially tailored nucleic acid molecule, or to boost a patient's deficient supply of functioning molecules...
...normal cell to become cancerous reported a significant step last week. A high-powered team of six investigators from the National Institutes of Health and Manhattan's Sloan-Kettering Institute announced that they had taken a virus that causes cancer in laboratory animals and had extracted the nucleic acid from the submicroscopic particles (only 1/100,000 mm. in diameter). This nucleic acid, when injected into test-tube growths of normal mouse cells, made them behave abnormally, as in cancer. The resulting cells, injected into hamsters, caused cancer every time. More strikingly, so did an injection of the nucleic acid...