Word: ocd
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...were given ketamine (colloquial name: Special K or usually just k). In the other study, a team led by Dr. Francisco Moreno of the University of Arizona gave psilocybin (the merrymaking chemical in psychedelic mushrooms) to obsessive-compulsive-disorder patients, most of whom later showed "acute reductions in core OCD symptoms." Now researchers at Harvard are studying how Ecstasy might help alleviate anxiety disorders, and the Beckley Foundation, a British trust, has received approval to begin what will be the first human studies with LSD since the 1970s...
...half-century later, scientists hope to unstitch psychedelic research from their forebears' excesses. Even as the Clinical Psychiatry paper trumpets psilocybin's potential for "powerful insights," it also urges caution. The paper suggests psilocybin only for severe OCD patients who have failed standard therapies and, as a last resort, may face brain surgery. Similarly, subjects can't take part in the Ecstasy trials unless their illness has continued after ordinary treatment...
...brain's emotion center. Paroxetine lowered activity there. As Toronto's Helen Mayberg explains, "Cognitive therapy targets the cortex, the thinking brain, reshaping how you process information and changing your thinking pattern. It decreases rumination, and trains the brain to adopt different thinking circuits." As with Schwartz's OCD patients, thinking had changed a pattern of activity--in this case, a pattern associated with depression--in the brain...
COULD THINKING ABOUT THOUGHTS IN A new way affect not only such pathological brain states as OCD and depression but also normal activity? To find out, neuroscientist Richard Davidson of the University of Wisconsin at Madison turned to Buddhist monks, the Olympic athletes of mental training. Some monks have spent more than 10,000 hours of their lives in meditation. Earlier in Davidson's career, he had found that activity greater in the left prefrontal cortex than in the right correlates with a higher baseline level of contentment. The relative left/right activity came to be seen as a marker...
...monks as well as the patients with depression or OCD, the conscious act of thinking about their thoughts in a particular way rearranged the brain. The discovery of neuroplasticity, in particular the power of the mind to change the brain, is still too new for scientists, let alone the rest of us, to grasp its full meaning. But even as it offers new therapies for illnesses of the mind, it promises something more fundamental: a new understanding of what it means to be human...