Word: offing
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Dates: during 1990-1999
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Cord-cell transplants have been performed for other blood diseases, such as leukemia, but they remain experimental and highly risky. Dr. Andrew Yeager, a transplant physician at Emory University medical school in Atlanta, warned the Penns that not only might Keone die, but there was not even more than a...
To prepare for the transplant, Keone had to undergo nine days of chemotherapy. The object was to kill his bone marrow, the source of his sickled blood cells, as well as to neutralize his immune system so it would accept the new cells. These came from an anonymous donor at...
The new cells seemed to take hold almost immediately, but for Keone the aftermath of the expensive ($200,000) treatment was like a death-defying roller-coaster ride. Again and again, he was readmitted to the hospital with fevers, diarrhea and loss of appetite, once for a six-week stay...
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Last week, on the first anniversary of the transplant, Yeager finally felt justified medically in pronouncing Keone cured. "The cord blood cells are now fully operational, making all healthy blood cells in Keone," he says. Equally important, there was no sign of sickle cells and no need for more transfusions...