Word: oklahomas
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...would have been a lot less shocking if McGee's vaccine trial had been run out of a back-alley clinic or a storefront in Tijuana. In fact, the study was conducted at the St. John Medical Center in Tulsa, Okla., and co-sponsored by the respected University of Oklahoma Health Sciences Center. It had been approved by the university's institutional review board, or IRB, a body set up to ensure that such trials meet federal standards for experimental design--including the obligation to inform participants of any safety issues. And it had been given the green light...
Unusual as it is, the Oklahoma case isn't an isolated incident--and in many ways, it isn't even the worst. Clinical trials are usually pretty safe; the vast majority of subjects are not hurt in any way. But so many problems--and such serious problems--have surfaced in recent years that doctors and hospital administrators are starting to wonder whether there is something dangerously wrong with the clinical-trial system...
...Oklahoma case, it may have been a nobler motive that tripped up McGee. "McGee is a good surgeon and a decent man," maintains his whistle-blowing research nurse, Mathias. "But he became a biased investigator. He thought he had found the cure for cancer. He really wasn't interested in running a clinical trial; he wanted to administer his drug"--even if that meant breaking the rules to get there. Although McGee said he had tested his drug properly on animals, he had not; the data he submitted in his original protocol came from animal studies of a different drug...
...Photo Essay: Just days before the scheduled execution of Timothy McVeigh, photographer David Leeson visited the Oklahoma City Bombing Memorial for TIME.com
...called brokenly for the parents they had left only minutes before. Most of their friends remained buried inside. The rescuers wept as they cradled them, limp and weightless; fire fighters could not bear to look down at the children in their arms. "Find out who did this," one told Oklahoma Governor Frank Keating. "All that I have found are a baby's finger and an American flag." That may turn out to be a poignant, gruesome icon. How easy it was to assume that the attack must have come from outside. America may no longer be safe from imported terrorism...