Word: oldest
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...Currently available ARVs work at both the beginning and the end of the HIV life cycle; the most recently approved class in 2003, called fusion inhibitors, start early, working to block HIV's attempt to bind and infect healthy cells to begin with. Next come the two oldest classes of drugs, which prevent the virus from transforming its genetic material from RNA to DNA. And finally, jumping to the very end of HIV's mission, the protease inhibitor drugs keep the virus from making its final protein coat, which it needs to re-emerge from the infected cell in order...
...They never bought a television and focused on ways to bring their family closer. It seems to have worked. While she is reticent on other topics, Karin Jentoft’s face spreads in a wide grin as she recounts classic family tales. Carla Jentoft calls her daughter and oldest son, Leif P. Jentoft, “best friends.” The siblings played and recorded together as a classical guitar duo until he left for Olin College, an engineering college in Massachusetts, two years ago. Now his sister has joined him in the Northeast...
...Harvard Square as the Pudding’s Woman of the Year. “For someone who never could have ever gotten close to getting into Harvard, I think this is even better,” Stiller said as he thanked the Pudding, the nation’s oldest undergraduate drama troupe, for the honor. But before he could be crowned the 41st Man of the Year, Stiller had to jump through a few hoops during the traditional roast, conducted by Pudding producers Evan W. Eachus ’08 and Scott A. Wilmore ’08.The roast...
...site, Kareem introduces himself as a 22-year-old law student studying in Al Azhar University, one of the oldest colleges in the world, soliciting his readers help against all forms of discrimination. In truth, Kareem had been expelled from the university in 2006 after clashing with the school's conservative administration. Azhar officials considered his blog writings too critical of the school and its religious scholars. Kareem then had difficulty enrolling in another law school. Describing his distaste for his Al Azhar University experience he wrote last October about the religiously-run instution's "infiltration of public life...
...Russian President Vladimir Putin himself. The short-lived replacements were all part of Russian ballet's insular old guard. "They were doing Sleeping Beauty the way it had always been done," says Andre Lewis, artistic director of Canada's Royal Winnipeg Ballet, North America's second oldest ballet company. "The Bolshoi was stultified. It needed to change...