Word: olestra
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Dates: during 1980-1989
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...moved closer to reality this month when Procter & Gamble dispatched a truck from its Cincinnati headquarters to the Food and Drug Administration in Washington. Its carefully guarded cargo: 30,000 pages of documents detailing tests of a new cholesterol- and calorie- free fat substitute that P&G calls olestra. The shipment included a petition asking the FDA to consider approving the substance's use in deep- fried foods, oils, shortenings and salty snacks...
...body without entering the bloodstream. Research at the University of Cincinnati appears to show that it can reduce a person's existing cholesterol levels. It supposedly satisfies what market researchers call the "mouth-feel" requirement that eludes so many yucky-tasting diet-oriented products. P&G, which has tested olestra on more than 1,800 people in the past 15 years, contends that foodstuffs containing it are as flavorful as those with the cholesterol-laden oils dear to so many American hearts, though perhaps not their arteries...
Despite extensive study, there is no assurance that unexpected side effects of olestra and other forms of SPE will not appear if the compounds go into wide use. Moreover, skeptics fear that many dieters will fill up on SPE-laden snacks and not eat enough natural foods with essential vitamins and other nutrients...