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...review published in the Jan. 20 issue of the Cochrane Database of Systematic Reviews, a leading evidence-based-medicine journal, researchers found that only one-third of 1% of chronic-pain patients without a history of substance problems became addicted to opioids during treatment. The review included 4,893 mostly middle-aged chronic-pain patients, who were treated with opioids for between six months and four years. "This suggests that people who do not have a history of drug abuse or addiction are not highly like to develop [addiction] under physician care," says Meredith Noble, lead author of the review...

Author: /time Magazine | Title: Are Doctors Too Reluctant to Prescribe Opioids? | 2/24/2010 | See Source »

...while the risk of opioid addiction in the elderly is low, there are other cautions. A study published in January by Von Korff and colleagues linked high-dose opioid use to a doubling of the risk of broken bones in the elderly. "One-third of these were hip and pelvic fractures," Von Korff says. "These can really be debilitating." The authors speculate that the patients may have been prone to falls caused by dizziness or sedation, side effects of drug treatment that tend to occur early in a new drug regimen or when dosage changes...

Author: /time Magazine | Title: Are Doctors Too Reluctant to Prescribe Opioids? | 2/24/2010 | See Source »

There's not much to fret about in simple particles of dirt or organic materials such as pollen (though they can trigger allergies), but lead, arsenic and DDT can be a more serious matter. About one-third of the arsenic in the atmosphere comes from natural sources - volcanoes principally. The rest comes from mining, smelting, burning fossil fuels and other industrial processes. Even in relatively low concentrations, arsenic is not without risk, especially to small children who play on the floor and routinely transfer things from their hands to their mouths. The same is true for lead, which comes less...

Author: /time Magazine | Title: What's in Household Dust? Don't Ask | 2/23/2010 | See Source »

...bars. But a court system that clobbers first-time offenders with mandatory sentences - sometimes for nonviolent crimes - will inevitably lock up thousands of not-so-bad guys alongside the hardened criminals. Not everyone agrees on the definition of a nonviolent criminal, but studies have estimated that as many as one-third of all U.S. prison inmates are in that category, most of them locked up on drug charges. (See the top 10 crime duos...

Author: /time Magazine | Title: What's Behind America's Falling Crime Rate | 2/22/2010 | See Source »

...One question left unanswered at Defexpo 2010 was whether a country in which one-third of the adults are illiterate and 43% of children are malnourished should spend so much on weapons. India's central government spent $4.5 billion on education in 2008 - about the same amount that it plans to spend on 197 new helicopters. A handful of protesters picketed outside the gates of the exhibition hall on opening day, but they drew little notice. India's attention is firmly focused on what a defense-company representative called the "quality gap" between its weapons and those of its neighbors...

Author: /time Magazine | Title: For the Arms Industry, India Is a Hot Market | 2/19/2010 | See Source »

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