Word: onset
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Dates: during 2000-2009
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Another gene, newly dubbed the parkin gene, has also been getting a lot of attention. In 1998 Japanese researchers reported on studies conducted on five young patients with early-onset Parkinson's, all of whom carried a recessive gene that appeared to be associated with the disease. Though relatively rare, the parkin gene is much more common than the defective alpha-synuclein gene, and in places like China, with high rates of early-onset Parkinson's, it may play a role in a significant number of cases. Just last October, researchers at Duke University Medical Center went a step further...
WALKING We already knew that walking can reduce adult-onset diabetes and coronary heart disease. But researchers at Harvard University have found another good reason to take a hike: to prevent stroke. According to the Harvard Health Letter, even people who had been sedentary for much of their life had a lower stroke risk soon after they started walking regularly. Speed counts, though. For the fastest walkers, the risk reduction was an impressive 40%. A leisurely stroll does some good, but the study showed that a brisk pace of three m.p.h. or more is the key, even more important than...
Gamma secretase emerged as an attractive target shortly after 1995, when scientists working with DNA donated by families prone to early-onset Alzheimer's disease finally succeeded in cloning two genes known as presenilin 1 and presenilin 2. In a series of experiments, researchers established that these genes exercised tight control over the activity of gamma secretase. They found that the particular mutations in the Alzheimer's-prone families not only increased the rate at which gamma secretase produces beta amyloid but also enhanced its penchant for making the more toxic version...
...consumed as much as 35 g of fiber a day were just as likely to develop precancerous growths in the intestines as those who were addicted to processed food. But fiber still has its benefits: it helps lower blood pressure, moderates cholesterol levels and combats type II (adult-onset) diabetes...
...against American naval vessels or the de-miners, it is clear that the embassy in Yemen, the Navy and the ship's captain were clearly aware of the threat environment, one that included precedent for attacking U.S. military interests and a national context of violently anti-American groups. The onset of Palestinian-Israeli fighting and Baghdad's renewed efforts to break sanctions should only have heightened concerns...