Word: onset
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Dates: during 2000-2009
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Consider what happened with Rezulin, the diabetes drug that was taken off the market last week. The FDA approved the medication in 1997 after tests on 3,000 people showed that it could help control Type 2 (formerly adult-onset) diabetes, which affects 15 million Americans. Although some test subjects developed abnormal liver reactions, no one suffered permanent damage, and no one died. Now that millions have taken Rezulin, however, it has been linked to at least 90 cases of liver failure, 63 of which resulted in death...
...important not to interpret these results too broadly. Herrington's study and its predecessor looked at women who already had ailing hearts. Both followed their patients for a relatively short time--three to four years. It's quite possible that estrogen is better at preventing the onset of heart problems than it is at treating existing disease. We won't know whether that hypothesis is valid for five more years, when a much larger study on the effects of estrogen in healthy women reaches its conclusion...
...vengeance. At Bayside, Zack's cell was a sure symbol of status. Nobody thought, however, that shiny Nokias and compact Motorolas would ever be anything but a modern means of communication and another way to look cool. Nowadays, the Qualcomm QCP-1960, among other impressive cellular instruments, causes the onset of malignant brain tumors. With excessive use, of course...
...Appearing now though, within America's favorite chain stores, is a newer and more user friendly type of little plastic card. With the onset of these "Gift Cards", customers now have the luxury of using plastic to spend money they they actually do have, which other credit cards simply can't provide. The Gap, JCrew and Tower Records have all wowed their shoppers with the emergence of their own unique versions of the "Gift Card," by minimizing the onset of buyers' remorse...
...early 1980s Lloyd's had begun to fear not only the onset of asbestos losses but future litigation arising from the recruitment drive. Its answer was to persuade Parliament to grant the company immunity from lawsuits by the Names--something the lawmakers might not do were they to get wind of the insurer's financial problems. And so, according to the London suit, Lloyd's duly set out to cook the books. The complex scheme allegedly involved closing the books prematurely on growing losses to conceal them...