Word: onsets
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...Census Bureau touted some optimistic news in its annual report on U.S. household finances, but ominous signs lurk behind the headlines. The 2007 data predate the full onset of the economic crisis, but some indicators warn of turmoil ahead...
Daley, who is also a professor at Harvard Medical School, said that he and his colleagues created 20 stable iPS cell lines from patients with genetic diseases including Parkinson's, Huntington's, Down Syndrome, juvenile-onset Type I diabetes, and two types of muscular dystrophy...
...reason for that delay in onset of cardiovascular disease could be that women are relatively iron-deficient compared to men - especially younger women, those in their late teens and early 20s - because of menstruation. Iron plays a very important part in the reactions in our cells that produce damaging free radicals, which glom onto cell membranes and DNA, and may translate into aging the cell. In fact, in our diets, red meat is the main source of iron, and lack of iron is probably one major reason that being vegetarian is healthy for you. There was a very good study...
Americans today suffer from an additional problem: obesity. If children are too well nourished, then they're not able to grow optimally. There are certain hormones that control the onset of the adolescent growth spurt and the onset of adolescence. Nutrition is one of the factors, along with genetic and hormonal ones, that are associated with the onset of puberty. Overnutrition prior to adolescence may affect the hormonal system and may produce too much growth hormone prior to puberty, so that sex steroids are produced earlier. And if that comes too early, then the youth will peak out sooner...
Drugs to treat this adult-onset condition would have to work differently from the ones used to treat fragile X syndrome because the biology of the disease is different too. In fragile X, the key gene is silent; in FXTAS patients, it's too active. "The gene produces up to 10 times more message than normal," explains molecular biologist Paul Hagerman of the University of California at Davis, who together with wife Randi has received an NIH grant to study the disorder. Over time, messenger RNA--the substance that transcribes genes into proteins--accumulates in the nuclei of brain cells...