Word: onsets
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With the twin obstacles of secrecy and mislabeling, the average lag time between the onset of the disorder and a proper diagnosis is now a shocking nine years, according to surveys of doctors conducted by the Obsessive Compulsive Foundation, a 21-year-old organization with headquarters in New Haven, Conn. It takes an average of eight additional years before effective treatment is prescribed. If the disorder strikes a young person, as it often does, that can mean an entire childhood lost to illness. "OCD has had a slow research start," says Gerald Nestadt, co-director of the OCD clinic...
What makes the glutamate-related gene especially suspect is the particular people it affects the most. OCD strikes males and females about evenly, but early-onset forms tend to target boys more than girls. This is particularly true in cases in which the boys also exhibit the involuntary tics or vocalizations often associated with Tourette's syndrome. Interacting with the glutamate gene are three genes related to androgens, or masculinizing hormones. Interacting with those is another gene that has been implicated in Tourette's. Gather all these together in the same chromosomal neighborhood, and they can make trouble. "Kids...
...Recently, fellow Firehouse dweller and local-access television celebrity Jayne Freeman asked me if I would be opposed to throwing a punk rock concert in the old engine garage. Blessed with such an ideal living situation and cursed with an inner early teen that refuses to embrace the onset of my 20s, I only asked: “Do you need help carrying in the beer...
...True, the onset of the G-8 meeting prompted Bush last week to announce new initiatives on climate change, fighting AIDS in Africa, and sanctions over Darfur. And the summit symbolizes the participants' willingness to work together to solve the world's major problems, for whatever that's worth. But policy discussion at the summit is largely symbolic. Bush would certainly have rolled out the AIDS money anyway, and he and Putin will meet elsewhere to talk about missile defense...
...that undertaking comes a lurking sensation that has taken hold of me and many on the precipice of our exeunt from the academy: that the placid narrow-mindedness dreamt up at Harvard will not survive the turbulent outside world. Today, we should be anxious, but exhilarated, by the onset of a reality beyond the collegiate kind...