Word: opiomelanocortin
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Dates: during 1990-1999
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...mice, at least, not to eat. Unfortunately, as reported last week in the Journal of the American Medical Association, it doesn't seem to work in humans. Researchers are still trying to figure out why not--and how to get around the problem. Another natural substance, called pro-opiomelanocortin (POMC), seems to signal that it's time to stop eating. Mice treated with POMC boosters shed 40% of their excess body weight in just two weeks. Again, it's not clear that this will work in humans, but it's conceivable that POMC therapy--perhaps in shots--could someday...
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