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...traditional medications, the brave new drugs will be designed "rationally" on computer screens, using gene information as a blueprint. VEGF2, for example, is a synthetic gene that makes a protein that in turn stimulates new vessel growth. In a few years, predicts William Haseltine, the biotech industry's champion optimist and CEO of Human Genome Sciences, based in Rockville, Md., we will have genetically based drugs for almost every serious ailment--"things we couldn't really work on well before, whether it's osteoporosis or Alzheimer's." Nor will these drugs simply attack symptoms, as aspirin does. "That...

Author: /time Magazine | Title: Got Any Good Drugs? | 11/8/1999 | See Source »

Snyder was not so sure. "I'm an optimist. Why would evolution have been parsimonious in depriving the human brain of the power of self-healing? I was a pediatrician before I became a neuroscientist. As a pediatrician, I was impressed by how much plasticity there really must be in the human brain. Pediatricians know that damage to the infant brain doesn't have the same outcome as damage to the adult brain. If a newborn has a stroke, even in the cortex [an area important to higher intellectual functions], he or she may sustain it and develop quite normally...

Author: /time Magazine | Title: Can I Grow A New Brain? | 11/8/1999 | See Source »

Purdy doesn't wish to be a spoilsport. He's negative only about negativity. Temperamentally, he's an optimist who places his faith in action, not attitude. One issue close to his tender rural heart is the preservation of West Virginia wilderness from the mountain-leveling predations of modern coal mining. A student of law and forestry at Yale, he sees himself arguing his causes in court someday, but his broader goal is to spur a resurgence in grass-roots public activism. "We need today a kind of thought and action that is too little contemplated yet remains possible...

Author: /time Magazine | Title: Books: Optimist In a Jaded Age | 9/20/1999 | See Source »

LAWRENCE JAMES CLARK Republican, North Carolina Resume: U.S. Army Relevant experience: Honorary deputy sheriff of Hardin County; member of Optimist Club Fraternal Organization, American Legion Platform: Reduce criminal appeals and expedite sentencing; improve literacy; see that Native Americans get their...

Author: /time Magazine | Title: Campaign 2000: Kooky Kandidates | 7/12/1999 | See Source »

Nobody foresees a continuation of the phenomenal 1998 rise in gross domestic product--a sizzling 6% annual rate in the fourth quarter, 3.9% for the year. But Cohen, true to her reputation as Wall Street's leading optimist, thinks the U.S. is in a "virtuous cycle" that will keep spinning, if a bit more slowly. The U.S., she notes, has created a stunning 15.5 million jobs since the end of 1993, even after subtracting job losses due to corporate downsizing. And two-thirds of these jobs pay more than the median wage for all U.S. jobs. By no coincidence, average...

Author: /time Magazine | Title: TIME Board Of Economists: Wall Street's Ghostbusters | 6/28/1999 | See Source »

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