Word: orale
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...disease. But in the absence of new evidence, the FDA's decision is likely to stand. Its impact has been enormous. The 34 protesters say that they will continue to use tolbutamide. But many other doctors, fearing possible malpractice suits, are refusing to write prescriptions for oral antidiabetes drugs of any kind...
...disagreement began last June when the FDA received a sobering report from the University Group Diabetes Program, an organization of twelve medical schools that had been studying the oral drug. The study, which followed 823 diabetics for eight years, found that the death rate from cardiovascular diseases was twice as high among patients on tolbutamide as it was among those on insulin treatments or placebos. As a result, the FDA recommended that tolbutamide be used only in cases in which the established treatments−dieting and insulin injections−had proved ineffective...
...unprecedented interference with the practice of medicine," and charged it with damaging the welfare of a million diabetics. As for the U.G.D.P. report, they noted that all diabetics are susceptible to cardiovascular disease. The study included unusually sick diabetics, they argued, so it was unfairly weighted against oral drugs. Because the raw data are still unpublished, the protesters added, the findings are almost impossible to refute...
...gets around. There is a girl who stages a whole strip show in her home for his benefit; when this and an extended attempt at oral stimulation fail to get him going, she tries talking about politics to excite him. There is a rich girl tripped out on acid. And a married girl from Grosse Pointe who was "thrown out of high school for giving blow jobs in the cafeteria" and now wouldn't mind being raped, with her husband for an audience...
...call your seatmate Charlie O. (for Oral). He is not just a minor nuisance, but the personification of a major menace. People today tell complete strangers things they once wouldn't have confessed to a priest, a doctor or a close friend: their crudest fears; their most shameful inadequacies; their maddest fantasies. We are witnessing something like the death of reticence...