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...shapes. They also detect and destroy improperly folded proteins that can cause such aging-related ailments as Huntington's disease. Other genes affect the transport of fat around the body--which may also have an effect on aging--and create proteins that kill invading microbes. "It's like an orchestra," says Kenyon. "The conductor is the hormones. You have the flutes as the antioxidant genes. The violins would be the chaperones, the cellos the metabolic genes. And maybe the drums would be the antimicrobial genes. So many different kinds of genes can have enormous effects on life and death...

Author: /time Magazine | Title: Diet Restriction: Eat Less, Live Longer? | 8/30/2004 | See Source »

...circuit for over a decade, Le Hogon, tel: (223) 223 0760, is managed by the amiable Moussa Yaffa, a DJ who mixes techno with the kora, or traditional harp. The club's best performers include Toumani Diabate, considered the world's greatest kora player, and the 22-piece Symmetric Orchestra, whose complex, swirling melodies are produced by the balaphon (a West African xylophone), djembe, kora and guitars...

Author: /time Magazine | Title: Time Traveler: One Nation Under a Groove | 8/16/2004 | See Source »

...later that Rex had said to our director, Moss Hart, "You either get rid of that kid, or I go," but I didn't know that at the time. Rex was nervous for a very different reason: he had never sung before and didn't think he could. The orchestra was very daunting for him, and so he demanded the most enormous amount of time. I felt left out of the loop. The miracle was that Moss must have seen something in me when I didn't see it in myself. He dismissed the company from rehearsals for a long...

Author: /time Magazine | Title: A Fair Lady | 8/16/2004 | See Source »

...fixture on the Bamako circuit for over a decade, Le Hogon is managed by the amiable Moussa Yaffa, a DJ who mixes techno with the kora (traditional harp). The club's best performers include Toumani Diabate, considered the world's greatest kora player, and the 22-piece Symmetric Orchestra, whose complex, swirling melodies are produced by the balaphon (a West African xylophone), djembe, kora and guitars. tel: (223) 223 0760 DJEMBE: Rough-edged Djembe may have been around longer than Le Hogon, if the '70s-style decor is anything to go by. Nonetheless, it's a reliable venue...

Author: /time Magazine | Title: One Nation Under a Groove | 8/15/2004 | See Source »

...Limbaugh is a big fan. Romantic Melodies, a recent CD that scored the biggest week-over-week sales increase in Billboard history, was scorned by one critic for "anesthetic properties (that) would surely soothe ... in a proctologist's waiting room." Another compared Mannheim's violin-heavy harmonies to an orchestra twirling a thousand rolls of toilet paper in the air at the same time...

Author: /time Magazine | Title: Entertainment: Stoking the Steamroller | 8/9/2004 | See Source »

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