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...syndrome, a fatal condition said to affect one in 12,000 newborns. In children with this defect, the left side of the heart, including its main pumping chamber, the left ventricle, and the aorta, is seriously underdeveloped. In Fae's case, doc tors said, the left side of the organ was virtually nonexistent...
Following what is now standard practice in heart transplants, Bailey transferred his tiny patient to a heart-lung machine, using it to gradually lower her body temperature from 98.6° F to about 68° F. The lower temperature slowed the baby's metabolism, allowing her other organs to better tolerate a reduced blood flow. One hour and 45 minutes into the operation, Bailey descended three floors to the basement, where the hospital maintains a colony of 29 primates. There, he removed the walnut-size heart of a seven-month-old female baboon, the animal that had proved...
...Christiaan Barnard, the South African pioneer of heart transplants, made two attempts to use simian hearts: in a 26-year-old woman, who survived for only six hours, and in a 59-year-old man, who died four days after surgery. In each case, Barnard "piggybacked" the animal organ onto the patient's own heart to act as a supplementary pump. He decided to abandon the technique because of the poor results and the risks of becoming "emotionally attached" to donor chimpanzees, which, he says "are very much like humans." Barnard is nonetheless enthusiastic about the Baby Fae case...
...general, the obstacle to using animal organs is that the human body quickly rejects foreign tissue. What gave Leonard Bailey hope of better results was the advent of the wonder-drug cyclosporine. Developed by Sandoz Ltd. in Switzerland, cyclosporine inhibits organ rejection by partly suppressing the immune system. It is considered safer than earlier drugs used for this purpose because it is less likely to destroy the body's ability to fight infection. Since its first use in the U.S. in 1979 it has revolutionized transplant surgery, raising the one-year survival rate of heart recipients from...
...open now on Saturday nights. Sports and sitcoms illuminate the color TV. Lizards skitter down the screens on the porch, and alligators slither down the canal just beyond. Now and again someone will have a go at the organ, and Father Jim will sing in his tenor, "No more will I go all around the world,/For I have found my world in you!" There are 630 members of Henry's Hideaway...