Word: ovarian
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Dates: during 2000-2009
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...Stephanie Yarber, who received a diagnosis of premature ovarian failure at age 14, conceiving children the old-fashioned way was a life's wish. In 2003, after several unsuccessful - and costly - courses of in vitro fertilization (IVF) using her identical-twin sister's donated eggs, Yarber began looking into other options. There was adoption, of course. But there was also a riskier experimental alternative: ovarian transplantation...
...Silber remembers the day he first spoke to Yarber. Her enthusiasm was contagious. But despite his vast experience with microsurgery and his success with male patients (he had also performed the world's first vasectomy reversal), Silber knew that all previous ovarian transplants in the U.S. had failed, as had those performed abroad. Still, he thought, in theory the procedure was possible. Yarber's surgery was scheduled for April...
...battle to preserve and prolong women's fertility has become increasingly visible of late. While advances in techniques like cryopreservation (the freezing and storing of eggs and embryos, for example, and now also ovarian tissue for transplants) have increased many women's chances of pregnancy, IVF is still a time-consuming and expensive process - and one that holds no guarantees. Success rates with IVF parallel fertility rates in the general population, dramatically declining with age. After 40, success rates drop to as low as 23%, and after age 43, Silber says, pregnancy is very rare...
...other fertility treatments - including experimental procedures such as harvesting immature eggs and maturing them in vitro for IVF, and the transplantation of ovarian tissue or entire intact ovaries - have gained ground in the past five years, especially for women with premature infertility or infertility resulting from cancer therapy. An article published in the Feb. 26 issue of the New England Journal of Medicine urges oncologists to consider fertility preservation, including the use of experimental techniques, more routinely with their patients, since as many as 90% of women who undergo full-body radiation become infertile. But even as fertility specialists offer...
...McCain had to make it clear he'd protect those programs from cuts. He made a similar exception during his anti-poverty tour in April, when he visited an African-American community in Alabama that got ferry service through an earmark. He then met a Pennsylvania woman with ovarian cancer who was being treated through a clinical trial funded by an earmark; he assured her that program was worthwhile too. "It's the process I object to," McCain explained...