Word: ovarian
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Sweeney's medical prognosis is good--her lymph nodes were cancer free, and doctors tell her there is little chance the cancer will recur. But her ordeal is eerily reminiscent of that of another former SNL cast member: Gilda Radner, who died of ovarian cancer in 1989. The two had the same dressing room at SNL and the same doctor at Cedars-Sinai Medical Center, and oddly, just before Sweeney got her cancer diagnosis, she had agreed to appear at a benefit for the Gilda Radner Foundation to fight ovarian cancer. "I feel guilty talking about her, because it seems...
...other hand, provides information that gives women many options. Unlike the Huntington's gene, BRCA1 is a "predisposing" gene; it increases vulnerability to cancer but does not make it inevitable. While the gene apparently confers an 85% risk of developing breast cancer and a 40%-to-60% risk of ovarian cancer, women who test positive may reduce that risk considerably, says Mark Skolnick, who led the team at Salt Lake City's Myriad Genetics that isolated the gene. He suggests they adopt a program that includes, among other things, exercise and a low-fat diet, and that they avoid doses...
...class of drugs that damage the DNA molecule by plastering it with sticky cross-links, thus triggering the suicide sequence. By contrast, the taxoids--including taxol, the compound isolated from the bark of the yew tree that was approved by the Food and Drug Administration as a weapon against ovarian cancer in 1992--cause the same suicidal result by deactivating a molecular machine that, just before cell division, separates the DNA in each chromosome into two separate strands. Still other drugs known as topoisomerase-1 inhibitors block a slightly earlier step in the DNA replication process, the uncoiling...
...studies involving immature eggs, surely the most controversial--and, to some ethicists, downright repugnant--is the work on ovarian tissue. Researchers have been performing experiments aimed ultimately at transplanting such tissue from fetuses--either aborted or miscarried--into infertile women. Fetal tissue is a rich source of eggs. A five-month fetus has cells that can produce about 7 million eggs, in contrast to the mere 400,000 or so that survive to a woman's puberty. Researchers have suggested using this tissue to establish egg banks for infertile women, who could then give birth to children...
...Most women undergoing surgery for early stage OVARIAN CANCER are not thoroughly checked to see if the disease has spread to their abdomen and lymph nodes, a study shows. The step can make the difference between life and death...