Word: overeater
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Dates: during 2000-2009
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...suspected just how powerful a role the bones play in so fundamental an activity as regulating sugar. Over a period of three years, Karsenty's team conducted a series of experiments with eight strains of mice, including some genetically altered to lack osteocalcin and some engineered to overeat. He found that osteocalcin significantly impacts how the body handles glucose, its primary fuel, in three ways: by raising the number of insulin-producing beta cells in the pancreas, by directly boosting the output of those cells, and by raising the body's sensitivity to insulin...
Finding a substance that increases beta cells, says Karsenty, "is a holy grail for diabetes research. If what's true for mice proves true for humans, "then we have inside us a hormone that does precisely this." In mice that are programmed to overeat and mice that are fed fatty diets, high levels of osteocalcin prevented both obesity and diabetes. Karsenty is now examining whether giving diabetic mice osteocalcin will reverse the disease...
...David Pierce, researchers at the University of Alberta studied the eating habits of young rats, and found that they tended to overeat when they were fed "diet" foods. Though the new study was conducted in animals, it adds to a growing body of research in humans that suggests a diet-foods paradox: the more low-calorie (or even zero-calorie) sodas and foods you consume, the more your body demands payback for the calories it was deprived...
...argues that people are manipulated into eating “mindlessly” by invisible forces outside them, ranging from atmosphere to eating companions to dish size. “Mindless Eating” endeavors to teach how to “remove the cues that cause you to overeat and how to reengineer your kitchen and your habits...
...holiday buffet, you're way more likely to overload your plate. What people should do at buffets is never have more than two items on their plate at any one time. They can go back as many times as they want. This really limits people's tendency to overeat...