Word: oxygenation
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Dates: during 2000-2009
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...pictures of the Buddha, their robes drenched with the late-monsoon rains. They walk briskly, stopping briefly to pray when they reach Sule Pagoda. Then they're off again, coursing through the city streets in a solid stream of red and orange, like blood vessels giving life to an oxygen-starved body. Their effect on Rangoon's residents is electrifying. At first, only a few brave onlookers applaud. Others clasp their hands together in respectful prayer or quietly weep. Then, as people grow bolder, the monks are joined by tens of thousands of Burmese, some chanting their own mantra...
...HUPD responded to a report of hazardous conditions at the School of Public Health. The reporting party stated that a cylinder filled with oxygen had a broken cap, was highly flammable, and was in close proximity to a possible flame. The Boston Fire Department, the Boston Police Department, the Boston Police Hazardous Materials Response, and the Massachusetts D.E.P. all responded to the scene. The room was sprayed with water and the second floor of the building was closed overnight...
Their finding, reported this week in the Proceedings of the National Academy of Sciences: nitric oxide (NO). A workhorse of the blood, the gas helps red blood cells ferry oxygen to tissues and props open tiny vessels to allow freer blood flow. It turns out that within hours of leaving the body, levels of nitric oxide in the blood begin to drop, until, by the time donated blood expires after 42 days, the gas is almost nonexistent. "The reality is that we are giving blood that cannot deliver oxygen properly," says Stamler, lead author of the study. "Many patients...
Previous trials have shown that heart disease patients, for example, who receive a blood transfusion to help restore oxygen to deprived tissues, have a 25% chance of having a heart attack and an 8% chance of dying within 30 days; similar patients who do not get transfused have an 8% chance of a cardiac event and a 3% chance of death. Stamler hypothesizes that without NO, red blood cells cannot drill their way into tiny blood vessels; rather, they pile up in narrow passageways, blocking blood flow instead of increasing it and hampering the heart...
...death from transfusion dropped dramatically, at least in mice. And there's reason to believe such replenishment could work in human patients as well; already, premature babies born with lung and respiratory problems are placed in NO-rich environments to ensure that their still developing tissues get the oxygen they need to grow properly. For now, the American Red Cross, which oversees 14 million units of banked blood, is waiting for additional study results before changing any of its processing and storage practices...