Word: oxygenation
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...processes that allow the body to turn food and air into nourishment for individual cells also create by-products that amount to toxic wastes--highly reactive oxygen molecules known as free radicals that can combine with otherwise innocent substances and transform them into killers. Free radicals may be responsible in part for the genetic damage that leads to some cancers. And they also appear to be what makes LDL and triglycerides so dangerous. When a free radical combines with one of these fatty molecules, the altered cholesterol turns into a biochemical cannonball that ricochets around the bloodstream, damaging the inner...
...their tenth week on Mount Everest, and it was their third attempt at reaching the summit. With the summit close at hand, the team saw a man shivering uncontrollably from the bitter cold and sitting three feet from a 10,000 foot precipice. The man, delusional from lack of oxygen, was pulling off his protective clothing. He was wearing no oxygen mask, no gloves, and no hat. “I bet you’re a bit surprised to see me here,” the man said quite lucidly, as the crew approached him, according to Osborne...
...airline seats, it came to be known as economy-class syndrome. (Former Vice President Al Gore, however, developed DVT in aircraft with plenty of leg room while he was campaigning for the presidency.) Many doctors suspected that the clots might be caused by low air pressure or changes in oxygen concentration during flight, in part because mountain climbers are known to develop DVT at high altitudes. But no one knew for sure...
...Journal of the American Medical Association caused such a stir. Scientists in Scotland asked 73 healthy volunteers to spend eight hours in a hypobaric chamber in conditions that simulated a plane flying at nearly 8,000 ft. Blood drawn after the test showed no evidence that air- pressure or oxygen levels had activated the clotting mechanism...
...help control the spread of cancers like leukemia that flare from the blood to the bone marrow and other tissues. Blocking a stem cell's source of nutrients might be another effective strategy for drug development. Unlike normal stem cells, which tap into many different blood supplies for the oxygen and growth factors they need to survive, cancerous stem cells seem to have more addictive personalities, zeroing in on one source and siphoning off everything they need. Exploiting that dependency by finding and cutting off the source would provide another way to tackle malignancies...