Word: paged
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Dates: during 1950-1959
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Partitioned Patient. What has worried Dr. Page most is that overspecialized modern medicine has not organized itself properly over the years to take broad-front action. Not only the disease but the patient has been senselessly partitioned. A man's brain, if he had a stroke, was in the province of the general internist. The gangrenous toes of his friend who suffered from Buerger's disease went to the angiologist. His heart belonged to the cardiologist, who grudgingly took responsibility for high blood pressure-but could do little for it. His kidneys were annexed by the urologist. Pleaded...
Surveying the puzzling and contradictory evidence, Dr. Page offers a moderate summation: too much fat in the diet and too little are both bad. Anything below 15% is dangerous (he tried it himself for a year and found that he lost weight, energy and equanimity). Current U.S. levels are needlessly high. A nice balance: 25%. And he sees no decisive difference in the effects of vegetable and animal fats...
...Question of Filtration. Then there is a little-known aspect of human circulation on which Dr. Page and others have been working. It may go far to solve the riddle of how atherosclerosis begins. In addition to the direct blood flow down the bore of the arteries to its destination in the capillaries, parts of it also perfuse through the arterial walls. Thus they reach many of the body's tissues and supply them with nourishing chemicals...
Bedside & Laboratories. Page began his work in 1937 at the Lilly Laboratory for Clinical Research at Indianapolis City Hospital, after three years at Munich's Kaiser Wilhelm Institute and six years at the Rockefeller Institute. With Canadian-born Dr. Arthur Curtis Corcoran, who has been teamed with him since 1936, Page made important discoveries on the workings of renin,* an enzyme secreted by the kidney when it is starved of blood. An injection of renin raises the blood pressure. It also alters the fat-protein combinations in the blood in such a way as to encourage atherosclerosis...
Since 1945, Page has been research chief of the Cleveland Clinic (a private medical center founded by the late Surgeon George Crile). In seven floors of laboratories, Dr. Page and his staff (eight physicians, four other research scientists, 26 technicians) are attacking all phases of hypertension from as many angles as possible, and in 20 research beds in the clinic's adjoining hospital the medical staff cares for patients who agree to cooperate in the study and treatment of their disease. Some of the scientific attacks are so basic that they seem remote from bedside medicine...