Word: paines
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Dates: during 1990-1999
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...pain killers now in use have drawbacks. Morphine, codeine and related drugs, given by mouth or intravenously, can cause such side effects as nausea, constipation and itching. Epidural blocks can lead to similar problems. In addition, they must usually be removed before the patient goes home, even though he or she may still be in pain. Berde has found that many people are reluctant to take pain medication at home, or give it to their children, in the mistaken fear that they will become addicts...
...problem might be solved by long-acting local anesthetics. Berde and his colleagues at Harvard and the Massachusetts Institute of Technology have patented time-release beads that contain a commonly used drug, bupivacaine. Injected into a surgical incision, the microscopic beads may block pain for a week, possibly reducing or even eliminating the need for opiates. The hope is that they will enable patients to recover sooner. The beads are being tried on patients overseas, and Berde expects testing in the U.S. to begin soon...
...years. "He is a master of the chemistry, of mixing the drugs to keep them comfortable." For families who wish to keep a dying child at home, she has known him to spend hours on the telephone with pharmacists and home-care nurses to come up with the right pain medicines...
...unusual, says Scopton, for Berde to go home to say good night to his children--David, 12, and Anna, 9--and then return to the hospital to take care of a child who needs help, particularly one who is dying of cancer and in great pain. It is also not rare for him to get a 3 a.m. phone call from, say, India for a consultation about some young patient in pain. "He has worked almost every day of the week almost since I've known him," says his wife Evelyn...
Seven years have passed since Alex Uihlein was treated at Children's Hospital, but Berde remembers him well. "He arrived in severe pain, essentially confined to a wheelchair, and if anyone moved his legs or touched them, he would cry and scream," Berde says. "He was withdrawn and just in very, very bad shape." Alex viewed Berde warily. "I was sick of dealing with doctors who didn't understand," Alex says now. But he found Berde different. For one thing, Berde listened. "He did understand," Alex says. "He believed in me, so I believed...