Word: paines
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Dates: during 1990-1999
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...main character summing up the importance of the film in an ostensibly stirring speech. It also take a renegade view towards violence. The director, Robert Benigni, makes it clear that people are about to die and spares us the gore. As a result, Benigni creates more sympathy for their pain than the desensitizing violence of Hollywood murders...
Chances are you've had plenty of dealings with those irksome little enzymes cyclooxygenase 1 and cyclooxygenase 2, better known as cox-1 and cox-2. They're what you suppress every time you take an aspirin. Trouble is, aspirin, ibuprofen and other over-the-counter pain killers wreak havoc on the stomach lining--and kill thousands every year through internal bleeding. So last week, an FDA advisory panel gave the green light to Celebrex, the first of a new breed of drugs called cox-2 inhibitors that promise to deliver all the relief of today's pain killers with...
...manufacturer can't just muscle its way into the $5 billion pain-killing industry and not expect resistance. Even before the FDA acted, the cox-1 forces were faxing inflammatory press releases to all takers...
...principle behind the new drugs is that when pain comes calling, it's all cox-2's doing. Cox-1, which wasn't known to be a separate enzyme until 1990, is supposed to be an innocent bystander responsible for "housekeeping" functions--like preventing ulcers. At the FDA meeting, proponents of the old-style pain killers suggested that that theory might be too simplistic. "The whole area of information about cox-1 and -2 is an evolving field," says Dr. Robert Palmer of SmithKline Beecham, which manufactures Relafen, a popular arthritis drug. "There's probably a whole lot of functions...
...other band members. At one point, he challenged Natasha Joseph, double second player and the lone woman in the group, to a little duel. While she lacked Gulston's dynamic stage presence, she showed him what was up as he, dripping sweat and looking as if he was in pain, tried to stump her with his instrument. Joseph was flawless as she effortlessly repeated his tunes, smiling. As mentioned earlier, most of the band members can play all of the instruments; they would switch repeatedly throughout the performance. Sheldon Webster especially, who is Gulston's partner on the tenors...