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...June 30 vote by a Food and Drug Administration (FDA) advisory committee to lower the maximum dosage of over-the-counter drugs containing acetaminophen and eliminate prescription acetaminophen-combination painkillers raised questions about what changes consumers should expect in the availability of the popular drug. The commonly used pain- and fever-reliever known as Tylenol is found in several nonprescription cough and cold remedies, including NyQuil and Theraflu. Patients are also asking what potential dangers their daily use of acetaminophen may pose. TIME.com talked to members of the FDA committee as well as pain experts to sort through some...

Author: /time Magazine | Title: The FDA and Painkillers: What's Safe Now? | 7/3/2009 | See Source »

...asked to vote ("Do you recommend eliminating prescription acetaminophen combination products?") can be interpreted in two ways. A yes vote could indicate elimination of the product altogether, but it could also indicate elimination only of the pairing of acetaminophen and a narcotic (like hydrocodone or oxycodone), the other primary pain-relieving ingredient contained in Vicodin and Percocet. "The question did not specify, so conceivably panel members could have had different interpretations," says Ruth Day, director of the medical cognition laboratory at Duke University and one of the voting panel members. "However, there was a lot of other discussion about having...

Author: /time Magazine | Title: The FDA and Painkillers: What's Safe Now? | 7/3/2009 | See Source »

...fill my prescription for Vicodin or Percocet? Yes. While the FDA usually follows the recommendations of its advisory panels, the recommendations are not binding. Even if they were, they would not take effect without careful consideration by the FDA of patients who currently rely on these medications for pain relief. "Any change would be carefully orchestrated to ensure that people are not at risk of not having access to their pain medication," says Dr. Judith Kramer, an internist at Duke University Medical Center and a voting member of the committee...

Author: /time Magazine | Title: The FDA and Painkillers: What's Safe Now? | 7/3/2009 | See Source »

Should I switch from Tylenol to aspirin or ibuprofen? Not necessarily. If you are not taking any other prescription pain medications that contain acetaminophen and you take Tylenol as directed, you should not be at risk of damaging your liver. Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) are effective pain relievers, but when taken at high doses and for prolonged periods - especially for the treatment of chronic pain in older adults - they carry a risk of stomach ulcers and gastrointestinal bleeding. NSAIDs may also raise blood pressure and affect kidney function. If you are concerned about your acetaminophen...

Author: /time Magazine | Title: The FDA and Painkillers: What's Safe Now? | 7/3/2009 | See Source »

...acetaminophen safe to take every day? Many people take Tylenol daily to relieve pain from chronic conditions such as arthritis, or they take Tylenol PM regularly to help them sleep. If taken as directed, doctors say these products are safe. At issue is the maximum daily dosage, which people may inadvertently exceed when taking a combination of medications that contain acetaminophen. Most people do not realize that the ingredient is present in so many different popular over-the-counter remedies...

Author: /time Magazine | Title: The FDA and Painkillers: What's Safe Now? | 7/3/2009 | See Source »

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