Word: paining
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Dates: during 2000-2009
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...momentum during Max's time with the wild things. At a certain point, I felt I'd learned enough and was ready to go home to Keener's anchoring presence. It's not that Jonze is overindulgent; it's that he's so thoroughly devoted to exploring Max's pain and joys, sometimes to the detriment of narrative. But I'll let my own child make the call on whether it's too long. I'm taking him, although I'd doubted I would, having expected the hipster's Max. But this is a Max for everyone...
...Pain study, which was led by Italian neuroscientist Martina Amanzio, reviewed 73 clinical trials conducted between 1988 and 2007. All the previously published trials pitted potential antimigraine medications against sugar pills. The medications included nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin and ibuprofen (Advil); triptans, which include Imitrex; and anticonvulsant drugs like Topamax. Those three categories of drugs carry different adverse effects: NSAIDs, for instance, often cause stomach problems; anticonvulsants can cause paresthesia (tingling) and memory impairment. Interestingly, patients who took sugar pills tended to report nocebo problems consistent with whatever drug they thought they might have swallowed...
...possible that the nocebo response is easily explained: in the antidepressant trials, maybe some patients - given that they already tended toward depression and anxiety - worried so much about the doctor's cautions that their stomach released enough acids to cause pain. That would make sense except that the range of possible nocebo responses stretches far beyond stomachache (in extreme cases, ailing patients who are mistakenly informed that they have only a few months to live will die within their given time frame, even though postmortem investigations show that there was no physiological explanation for early death). In a new paper...
...Pain study found that date of publication had no effect on the side effects reported: the placebo and nocebo responses were just as robust before 1997 as after. That leaves scientists still looking for an answer. The Wired story suggested that the act of merely doing something good for yourself may stimulate the body's "endogenous health-care system," perhaps by inhibiting stress hormones. But that wouldn't explain why the same act might lead to phantom nocebo aches and pains...
...York City on music and the brain. The son of a world-renowned cellist, Janigro specializes in studying epilepsy and is associated with Cleveland Clinic's Arts and Medicine Institute, which is working to advance our understanding of how music can do such things as help decrease pain and blood pressure and improve movement in Parkinson's patients...