Word: panicali
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Dates: during 1980-1989
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What Paoletti and his colleague, Virologist Dennis Panicali, set out to do was to alter the genetic material, or DNA, of cowpox virus by inserting a gene from another virus-herpes, hepatitis B or influenza (see diagram). The goal of these microscopic manipulations is to develop a vaccine that will fool the immune system and make it swing into action. A smallpox preventive that expresses a herpes trait, for instance, will provoke the body into creating antibodies against herpes. The person is then protectively armed against an actual attack of the disease...
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