Word: parathyroids
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Thus a person with an underactive thyroid need not take thyroxin the rest of his life. Nor need one with a deficient parathyroid forever take calcium-bearing drugs to ward off spasms. If Professor Stone can extend his system of culturing minced glands to include the pancreas and the adrenals, he indicated last week, surgeons would have a simple, permanent cure for diabetes and Addison's disease. But, warned the able doctor: "No type or method of grafting can reasonably be expected to yield 100% successful results...
Johns Hopkins' Professor Harvey Brinton Stone was cautiously vague last winter when he let it be known that he was successfully transplanting human thyroid and parathyroid tissue by new methods (TIME, Dec. 18). More sure of his methods this year, Professor Stone has been publishing the details of this difficult surgical procedure in the Annals of Surgery. By last week, when he was asked to tell the American College of Surgeons (see p. 35) what he was doing, he had achieved sufficient boldness to pack his whole story into a few simple sentences. Said...
...called myositis ossificans progressiva. Extremely rare in adults, it is almost unheard of in children. All physicians know is that some disturbance of Benjamin Hcndrick's metabolism has let increased amounts of calcium seep into his muscles and bones. Some think the disturbance may be in the parathyroid glands, which regulate the body's use of calcium and phosphorous. The disease, which produces circus sideshows' "stone men," is usually not fatal to adults, sometimes causing only a local ossification. Some physicians think there is a long chance of saving Benjamin Hendrick, whose back, thighs and upper arms...
...placed in proper containers under proper conditions, becomes a culture medium in which the gland tissue to be grafted is placed. The gland tissue gradually becomes accustomed to the serum, and thus to the biological character of its owner-to-be. When Dr. Stone finally fits a thyroid or parathyroid graft into a new body, the graft suffers no shock, takes firm and lasting root, grows and supplies essential hormones. In the Stone technique whole glands are not necessary for grafting. A few strong cells suffice, and their surrender causes the donor no discomfort...
...large significance to all sufferers from subnormal thyroid or parathyroid glands was last week's news from Johns Hopkins where Professor Harvey Brinton Stone has developed a method of cultivating grafts so that they take lasting hold in a new body. Thyroid and parathyroid happen to be the material which furnished him spectacular results. No longer did his hypothyroids and hypoparathyroids need glandular extracts. His method may apply to all kinds of tissue. Possibly diabetics and other glandular sufferers can get similar relief...