Word: parkinson
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...advances in treatment will probably result in only modest gains. Clinicians will be able to delay onset by several years and lessen the severity of symptoms. But by 2025, control could come to resemble a cure. For Alzheimer's has something in common with other brain disorders such as Parkinson's, Huntington's and mad-cow disease. Like them, it appears to be caused by misfolded proteins--in this case, beta amyloid and tau. And so one day in the 21st century it may become possible to vanquish Alzheimer's with a vaccine that targets these miscreants...
...medical science has had only mixed results with brain-cell transplants. Take the treatment of Parkinson's disease, for example, a condition that is gradually depriving more than 1 million Americans of their ability to move and speak. The disease is caused by the slow deterioration of brain cells that produce dopamine, a chemical essential for the transmission of messages from the brain to the rest of the body. A decade ago, Swedish researchers started implanting dopamine-producing cells from human fetuses into the brains of Parkinson's patients. The treatment improved the mobility of many of the patients...
...last play of the evening, Anton Chekov's The Marriage Proposal, stands in sharp contrast to the Pinter and Williams works. The physical comedy of Chekov's piece seems almost inconsiderate after the grueling emotional turmoil of Williams' piece. Director Aidan Parkinson takes a burlesque approach to Chekov's story of a marriage proposal interrupted by disputes over trivial family rivalries. Dorothy Brodesser returns in drag as the scowling father of Natalia, the woman whom Chekov's feeble hero Lomov wants to wed, and Barlow Anderson as Lomov reaches feats of physical hypochondria that defy description. Parkinson's production comes...
...different at first, but later on they realized what he did, how it was good..." A girl named Ellen picks up: "Once people prove they can win, they're all glorified." "Close," prods Mendelson. Another girl administers the coup de grace: "Muhammad Ali, the farther he got into Parkinson's--now he's harmless, and so they're not afraid of him anymore. He's like a Hester now that she's a good girl." Mendelson, triumphant: "Once an enemy of society has been defeated, we can embrace them and call her cute little Hester, cute little Muhammad Ali. They...
DIED. BERNARD BUFFET, 71, austere French painter whose dark landscapes and portraits (like the De Gaulle he did for Time, above) were inspired by postwar Paris; by his own hand, after a battle with Parkinson's disease; in southern France...