Word: parkinsonian
(lookup in dictionary)
(lookup stats)
Dates: during 1990-1999
Sort By: most recent first
(reverse)
...periphery of the American consciousness. There have been occasional revelations that public figures suffer from the illness, including Attorney General Janet Reno, the boxer Mohammed Ali and Pope John Paul II. And in 1990, the movie "Awakenings" illustrated with striking realism the physical incapacity of patients with Parkinsonian symptoms. But for whatever reason (perhaps because the public figures stricken with Parkinson's are in the expected age bracket for the disease and have not been vocal about their health), the illness does not have a high level of public awareness...
...role in sleep, mood, depression and anxiety. They have also discerned five different receptor subtypes for dopamine, a neurotransmitter thought to be involved in schizophrenia. By formulating compounds that selectively bind to particular dopamine receptors, for example, drug designers can craft schizophrenia drugs that curb hallucinations without triggering disabling Parkinsonian symptoms...
...dirty drug," says Mount Sinai's Davis. "It probably binds to a whole bunch of receptors. We used to think that was a bad thing. Now we think that's maybe a good thing." Perhaps because of its affinity for serotonin receptors, Clozaril is largely free of the Parkinsonian side effects (the "Thorazine shuffle" and so on) that plague the classic antipsychotic drugs. It was also the first drug to ameliorate symptoms of schizophrenia that are resistant to other drugs. But Clozaril has a major drawback: a life-threatening side effect called agranulocytosis, a drastic drop in white blood cells...