Word: parkinsonism
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Dates: during 2000-2009
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DIED. ALFRED KANTOR, 79, artist who rendered rare scenes of daily life in concentration camps; of complications from Parkinson's disease; in Yarmouth, Maine. As a prisoner at Auschwitz and other camps, Kantor destroyed many of his pieces just after painting or drawing them for fear of retribution. He then re-created scenes--of corpses, crematoriums, and guards--from memory...
Studies have established links between the incidence of depression and several other diseases, including cancer, Parkinson's disease, epilepsy, stroke and Alzheimer's. In some cases at least, researchers have clues, if not definitive evidence, as to which molecules might be involved. In Parkinson's, the problem is the death of cells in the brain that produce the neurotransmitter dopamine. While dopamine is crucial to the control of movement, it's probably a major factor in mood as well. "Depression almost certainly has multiple causes that produce similar symptoms," observes Dr. Bruce Cohen, president of McLean Hospital in Belmont, Mass...
That could explain why drugs that improve serotonin chemistry don't always work on depression--and why Parkinson's and depression can feed on each another. Epilepsy, stroke and Alzheimer's, which, like Parkinson's, involve physical alteration of the brain, probably also affect that organ's ability to make or process neurotransmitters--not only serotonin and dopamine but also glutamate and norepinephrine, all of which may be involved in different forms of depression...
...PARKINSON'S DISEASE More than 1 million Americans have...
DIED. GEORGE ROY HILL, 81, Oscar-winning director who brought a breezy touch to old-fashioned storytelling in some of Hollywood's most popular big-star entertainments of the 1960s and '70s; after a battle with Parkinson's disease; in New York City. A stickler for quality who made just 14 movies in a three-decade career, he popularized the duo of Robert Redford and Paul Newman in Butch Cassidy and the Sundance Kid (1969) and The Sting (1973) and made acclaimed film versions of Kurt Vonnegut's Slaughterhouse-Five and John Irving's The World According to Garp...