Word: parkinsons
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...neurotransmitter dopamine ranks among the most powerful of the brain's master molecules. A regulator of mood and movement, it plays a principal role in Parkinson's disease, drug addiction and schizophrenia. For years after its discovery in 1910, however, scientists considered dopamine merely a stepping-stone to the more powerful compound noradrenaline...
Carlsson's mice, in other words, resembled human patients with Parkinson's disease--and L-dopa, the dopamine-boosting compound he used to restore normality to the mice, soon emerged as the frontline treatment for Parkinson...
...REST OF US: When nerves in the brain can't communicate with one another, physical as well as psychiatric problems can arise. Carlsson and Greengard were instrumental in identifying the role of dopamine (a key brain chemical) as a transmitter, a discovery that has led to new treatments for Parkinson's and schizophrenia. Kandel's research showed that changing the speed of inner-brain transmissions can have profound effects on both short- and long-term memory...
AILING. PIERRE TRUDEAU, 80, rakish, quick-witted and charismatic former Prime Minister of Canada; with an undisclosed illness; in Montreal. Trudeau, who served from 1968 until 1984 (except for nine months when he was voted out of office), suffers from Parkinson's disease, and caught pneumonia earlier this year. According to his two sons, he is "not well" and "resting comfortably with his family...
Ever since they were first isolated two years ago, embryonic stem cells have been touted as a potential medical miracle. Diabetes, Parkinson's disease, Alzheimer's and spinal-cord injury are among the devastating maladies that might be treated by turning these versatile cells into healthy replacements for just about any damaged tissue, from the pancreas to the brain...