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...Oleanna seemed to grow out of the authentic passions of a particular time (just after the Clarence Thomas hearings), when sexual harassment and political correctness were ripe issues. Race, by contrast, seems like a relic of another era. The advent of Barack Obama may not have invalidated Mamet's cynical view of race relations, but it has made it seem shockingly glib and opportunistic. "This isn't about sex. It's about race," goes the exchange that brings down the curtain in one scene. "What's the difference?" Make sense of that line, and you just might be able...

Author: /time Magazine | Title: The Downward Spiral of David Mamet | 1/11/2010 | See Source »

Maze's research focused on a particular protein called G9a that is associated with cocaine-related changes in the nucleus accumbens, a brain region essential for the experience of desire, pleasure and drive. The role of the protein appears to be to shut down genes that shouldn't be on. One-time use of cocaine increases levels of G9a. But repeated use works the other way, suppressing the protein and reducing its overall control of gene activation. Without enough G9a, those overactive genes cause brain cells to generate more dendritic spines, which are the parts of cells that make connections...

Author: /time Magazine | Title: How Cocaine Scrambles Genes in the Brain | 1/8/2010 | See Source »

...Thursday in the journal Science Express, the paper describes a new algorithm that can identify mutations with a much higher resolution. The method, called "Composite of Multiple Signals", assigns a score to every mutation in a region and then ranks the probability of each mutation influencing the selection of particular traits...

Author: By Helen X. Yang, CRIMSON STAFF WRITER | Title: Harvard Researchers Use Innovative Method to Follow Genetic Footprint | 1/8/2010 | See Source »

When I am old and thoroughly demented, living in a nursing home, I feel certain I will grab the arm of anyone who passes to tell them about the time I took Michael Cera's virginity. This particular lapse will be forgivable - it may even become a trend among members of 21st century senile generations - because as moviegoers, we will all have been there with him for multiple attempts and some successes...

Author: /time Magazine | Title: Youth in Revolt: Michael Cera and His Evil Twin | 1/7/2010 | See Source »

...coupon for the items that you like if you're brand flexible. Maybe someone says, "I have to have Kellogg's Raisin Bran, I won't eat Post Raisin Bran." Even in respect [to] that kind of brand person, there is going to be a coupon for that particular brand at some time. So if it's that important to you to have that brand, recognize when it's at its lowest price and stock up on it. (See questions and answers about retirement...

Author: /time Magazine | Title: Coupon Mom: How to Cut Grocery Bills in Half | 1/6/2010 | See Source »

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