Word: patches
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...sellers, he has not had the runaway success of Ian Falconer's spunky little pig Olivia or President Bush's personal favorite, Eric Carle's The Very Hungry Caterpillar. Still, neither Falconer's nor Carle's works are being spun into anything nearly so ambitious as the Sunny Patch brand, Miss Spider's line of goods. Target, Callaway and Kirk think that doesn't matter. "Our core guest [i.e., customer] is a busy mom with young children. She's highly educated," says Sally Mueller, Target's director of marketing planning. "Many of our core guests have read David Kirk...
...antidepressants (such as Elavil and Tofranil) also blocked the absorption of neurotransmitters, especially norepinephrine, but the drugs had significant side effects. Another class of first-generation drugs, the monoamine oxidase inhibitors (MAOIs) such as Nardil and Marplan, can be effective but can also produce dangerous side effects. A transdermal patch just approved by the Food and Drug Administration will give new life to MAOIs by reducing the side effects they sometimes caused when taken orally...
...chemical signaling in the brain. Because they control so much of the brain's activity, the trick is to fine-tune their levels in ways that relieve depression but don't affect other brain functions. Other targets of drug development: the sex hormone testosterone (a transdermal patch proved effective in a recent clinical trial for men); the stress hormone cortisol, which researchers are trying to regulate with the abortion drug RU 486 and compounds called CRF antagonists; the dynorphins (the evil twins of feel-good endorphins); and a chemical called substance P, involved in pain pathways closely related to depression...
Dwarfed by the towering height of William James Hall and the concrete mass of the Graduate School of Design’s Gund Hall, the Swedenborg Chapel stands on a small patch of grass on the corner of Kirkland and Quincy Streets...
...Green Party, part of his ruling coalition, have warned that government support for an Iraq resolution would strain relations between rank-and-file Greens and party leaders, as well as relations between the Greens and Schröder's Social Democrats. Still, Schröder is keen to patch things up with Washington. He has agreed to allow U.S. forces to use bases in Germany and German airspace if war breaks out, and to provide troops to guard American installations in Germany, freeing U.S. soldiers for possible service in Iraq. Schröder needs American goodwill to pursue Germany...