Word: patentable
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Dates: during 1990-1999
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...deliciously catty mother Hannah (Lauren Bacall) and sister Claire (Mimi Rogers). A cross between a hopeless romantic and a mental case, Rose cancels all her dates with the weirdos who pursue her, and instead lays around in pajamas eating cookies and watching baseball. Barbra has had a patent pending on this role for decades, and she plays it with ease and style and old-fashioned Jewish humor...
Demon is sadly one of few satirical journals on the Harvard campus, providing the most patent vindication of Adam Smith's thesis that the quality of goods diminishes proportionately with a decrease in competition. Such "humor" would cease to intrigue if higher quality goods were available in our humor market. A few more humor magazines and Demon would be compelled by the rationale of supply and demand to undertake a wholly new and revolutionary enterprise: to create humor that is at the same time clean, engaging, tasteful and intellectual, or, at the very least, inoffensive...
...mifepristone. It has been available in Europe since 1988, but the French manufacturer, Roussel Uclaf, fearing harassment by militant antiabortionists, refused to market it in the U.S. In 1994, though, the New York City-based Population Council offered to take the heat and acquired the drug's American patent rights. After two years of clinical trials, the organization applied to the FDA for permission to sell the drug. In July an advisory committee recommended approval...
Meanwhile, Servier had finally figured out how to produce pure dexfenfluramine, without its mirror-image molecule. This was a potentially profitable discovery, since the patent on fenfluramine was about to run out, and the new formulation could be considered a novel, patentable drug. Servier approached Wurtman in the late 1970s with a proposal that he purchase the U.S. rights to dexfenfluramine. Wurtman tested the drug, found it was indeed effective and agreed. The actual purchaser would be Interneuron Pharmaceuticals, a company co-founded by Wurtman to market discoveries by M.I.T. scientists. Interneuron subsequently licensed the drug to Wyeth-Ayerst...
DHEA, by comparison, is the modern equivalent of a patent medicine--an interesting compound being sold as a cure-all on the basis of the flimsiest scientific evidence. Like human-growth hormone and melatonin, two other drugs being promoted as antiaging compounds, DHEA is a medically active chemical with real value that has piqued the interest of mainstream scientists. But the claims that surround DHEA--that it can restore sexual vigor, prevent cancer and heart disease, and add decades to your life--run far ahead of the science...