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...absorption of cholesterol in the gut, rather than regulating the fat's production in the liver, like other statins do. ENHANCE compared the effect of Vytorin to simvastatin alone, and showed little difference between the two medications when it came to plaque size in the arteries. Simvastatin came off patent in 2006, and these results suggest that the generic form of simvastatin may be as effective as the more expensive Vytorin...

Author: /time Magazine | Title: Is Vytorin a Failure? | 1/15/2008 | See Source »

...found some allies in the Chinese courts. Pfizer won a landmark trademark-infringement case in October when a Chinese court ordered a domestic company to stop using Pfizer's logo on its website and fined the offender $25,000. Novartis CEO Daniel Vasella, for one, cites China's "enlightened" patent laws as the reason the Swiss drugmaker will continue to invest in China vs. India, where a court recently rejected the company's attempt to protect a patent on a leukemia drug. "China has made tremendous progress and taken the steps to show they have the right priorities," he says...

Author: /time Magazine | Title: China's Drug Addiction | 11/14/2007 | See Source »

...wildlife from what they call "biocolonialism" or "biopiracy." The governments are drafting strict laws to ensure that the world's 300 million mostly poor tribal people share in the wealth that their knowledge helps create. One of the newer strategies is for governments or indigenous communities to obtain commercial patent rights on medicines and other products divined in animals and plants before the labs can muscle in. (None of the new laws are retroactive.) They also hope to make biocolonialism a key global trade issue at next month's meeting of the U.N.'s World Intellectual Property Organization in Geneva...

Author: /time Magazine | Title: Jungle Medicine | 11/14/2007 | See Source »

Many pharmaceutical firms have drawn criticism for extending their franchises through frivolous lawsuits blocking equivalent generic drugs that are much less expensive. To allow drug companies to recoup investments and collect healthy returns, the Hatch-Waxman Act of 1984 gives companies 20-year monopolies from the day they patent a product. (After that, revenues from a drug can drop as much as 80% within months as generics erode the market.) The law allows drug firms a 30-month monopoly extension to resolve patent disputes. That loophole is much abused. Companies often sue generic manufacturers just to buy time...

Author: /time Magazine | Title: Drug Lord | 11/13/2007 | See Source »

...based on the DNA sequence of the active bacterium Mycoplasma gentitalium. Their artificial chromosome was built entirely from available chemicals and has been christened, Mycoplasma labortorium. In theory, the chromosome could be transplanted into an empty bacterial cell and replicate itself thereafter. Synthetic Genomics has already filed for a patent on their “biological invention.” Scientists believe that they will soon be able to create “designer genomes,” promising synthetic bacteria that could curb global warming by breaking down atmospheric carbon dioxide or ease global energy needs by producing nonpolluting...

Author: By James M. Wilsterman | Title: New Life, New Rules | 11/8/2007 | See Source »

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