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Proposed in 1969 by Pathologist Kilmer McCully, then of Harvard, this thesis also implicates diet, but the villain is protein. Methionine, an amino acid, is broken down by the body into homocysteine, a chemical that promotes atherosclerosis (or the buildup of plaque in the arteries) in lab animals. According to the theory, it is converted by vitamin B6 into an innocuous byproduct, but if there is a deficiency of B6, homocysteine piles up in the blood and causes atherosclerosis. In the view of the theory's proponents, Americans are vulnerable to heart disease because the protective vitamin, which...

Author: /time Magazine | Title: Medicine: Diet Debate | 8/6/1979 | See Source »

...sweeten adversity, Shakespeare played up the toad's jeweled eye rather than its warts and bloat. Dr. William Ober, a Boston-born pathologist with an 18th century prose style and a tart Yankee wit, would rather dissect the toad. The eye looks out for itself; the rude and frequently ugly support systems of truth and beauty need all the help they can get. There is, of course, a long history of the artist as freak and invalid: Plato's ideas of divine mania; Philoctetes, the archer of Greek mythology, whose festering wounds made him unfit company; 19th century...

Author: /time Magazine | Title: Books: Second Opinions | 7/16/1979 | See Source »

...William's 'sense of humanity' was an approved value of that particular cultural trend. However, alternative views are possible ... I question whether an indiscriminate liking for people is a virtue ... Yet that may be one reason why Williams went into general practice, and I became a pathologist. He was willing to accept the world and people in it as they were; I reserve the right to review them under the microscope and look daily at their weaknesses, faults, malformations, and diseases...

Author: /time Magazine | Title: Books: Second Opinions | 7/16/1979 | See Source »

...Pathologist Paul Lacy and his colleagues at Washington University have devised a way to encourage islet survival-at least in laboratory animals. Taking healthy islets from rats, the team "incubated" them at room temperature for seven days, then injected them into diabetic animals, along with an immunosuppressive serum. More than 100 days later, the transplanted islets were still producing insulin in the diabetics, whose condition improved markedly. The next major question: Will this successful experiment in rats also work...

Author: /time Magazine | Title: Medicine: Puzzling Ailment | 6/25/1979 | See Source »

...showed in The Siege of Krishnpur (1974), British Novelist J.G. Farrell has a pathologist's instinct for the way such a deluded idyll turns into apocalypse...

Author: /time Magazine | Title: Books: Deluded Idyll | 5/28/1979 | See Source »

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