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...this a viable cure for HIV? Not by a long shot. Even Huetter says bone-marrow transplants, which kill about a third of patients, are so dangerous that "they can't be justified ethically" in anything other than desperate situations like late-stage leukemia. Nor is it clear that Huetter's claim to have cured his patient is yet justified. HIV has a frustrating ability to hide in hard-to-detect "reservoir" cells in various parts of the body. Current antiviral drugs, for example, can lower a patient's "viral load" to the point that HIV is undetectable...

Author: /time Magazine | Title: Can a Bone-Marrow Transplant Halt HIV? | 11/13/2008 | See Source »

...Huetter's patient has not received antivirals for two years and remains virus-free even in the known HIV hiding spots of brain and rectal tissue, according to Huetter's tests. But many researchers remain skeptical about whether these tests have been thorough enough. Dr. Andrew Badley, director of the HIV and immunology research lab at the Mayo Clinic, told the Associated Press, "A lot more scrutiny from a lot of different biological samples would be required to say it's not present...

Author: /time Magazine | Title: Can a Bone-Marrow Transplant Halt HIV? | 11/13/2008 | See Source »

...there might be a glimmer of hope in the case. If the transplant does prove to have been a success and can be replicated, researchers say gene therapists might one day be able to re-engineer a patient's cells to change their bone marrow the same way a transplant does, except without the dangers. Such a breakthrough, if it proves possible, would be "decades rather than years away," according to Ade Fakoya, a London-based clinician and senior adviser to the nonprofit Aids Alliance. The treatment would also likely prove too expensive to implement in developing countries where...

Author: /time Magazine | Title: Can a Bone-Marrow Transplant Halt HIV? | 11/13/2008 | See Source »

Three weeks later, his 47-year-old son Randy, also a dialysis patient and a heparin user, suddenly had symptoms similar to those that had killed his mother. Shockingly, he died on Jan. 15, as his wife Colleen, a dialysis nurse (they had met at the clinic years earlier), frantically and futilely tried to revive him. An uncomprehending family buried Randy Hubley next to his mother in Toledo...

Author: /time Magazine | Title: Heparin's Deadly Side Effects | 11/13/2008 | See Source »

...layman, David Shore, and although the show is purportedly inspired by medical columns from The New York Times and The New Yorker, it isn’t exactly clear on what distant reality the show is based. Unlike in “ER,” where innumerable patients must be treated at a moment’s notice, House is able to spend days diagnosing one patient and doing several trillion dollars worth of tests. In real life, hundreds of people would have died, waiting in triage, while House made cranky jokes about a man whose skin had miraculously...

Author: By Andrew F. Nunnelly, CRIMSON STAFF WRITER | Title: Paging Crichton, 'House' Hurting | 11/13/2008 | See Source »

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