Word: patient
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...very objective director. Her film is all show, no tell. It doesn't whine or speechify or make liberal-minded, quasi-political appeals for relief of its characters' hard lives. She lets us come to care for Ray at our own unforced pace, and Leo plays superbly in that patient vein. There's nothing overtly heroic about her as she plods forward under her burden of her small-scale dreams. She's not cynical, but she's not expecting much, either. She's just knowing and accepting of what fate, good or bad, but never transformative, throws...
...more discoveries are made, researchers hope they'll develop a better understanding of who is most at risk of Alzheimer's disease, how each patient's case is unique, and how best to treat specific patients with the drug and lifestyle changes that will be most effective for them. Taken together, these approaches could one day make the long goodbye of Alzheimer's a thing of the past...
Researchers also questioned whether iPS would work with delicate cells from older people or with cells taken from patients with disease (Yamanaka used skin cells from healthy middle-aged people in his study). Eggan and Henderson tackled both issues at once, by working with cells from two siblings, ages 82 and 89, who both had ALS. It turned out that generating iPS cells from older patients proved no more difficult than growing them from younger ones, says Eggan. "This study puts those issues definitively to rest," he says. "It opens the door to being able to make patient-specific stem...
...connect the spinal cord to the body's muscles and which degenerate in ALS. But researchers have not been able to prove that these cells will be clinically useful - that is, whether the new nerve cells will work as well as healthy ones in the spinal cord of a patient. Testing the viability of cells made from iPS stem cells is still a long way off, mostly because iPS requires the use of viruses to deliver the time-reversing genes into adult cells - that works in the lab, but it is not yet safe for patients. To use iPS cells...
Scientists from Harvard and Columbia announced Thursday the creation of the first patient-specific stem cell line from humans afflicted with a genetic disease, a key step in the push to create therapies for a wide variety of illnesses by replacing diseased tissue with tissue generated by stem cells...