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...experimental drug has successfully reduced hip and spine fractures in the two largest patient populations at risk for osteoporosis - postmenopausal women and men being treated for prostate cancer - according to two major studies published online on Aug. 11 by the New England Journal of Medicine. The new compound, denosumab, is being reviewed by the Food and Drug Administration. If approved, it has the potential to become a standard treatment for certain patients...
...much impact this would have on patient care remains to be seen," says Dr. Sundeep Khosla, a professor of medicine at the Mayo Clinic, who wrote an editorial accompanying the two studies in the Journal. But because denosumab did not result in any serious side effects, it has the potential of becoming a safer alternative, should its current profile hold up in additional studies...
...work with it only in biosecurity Level 4 laboratories, the highest level of biological containment available. So far, H5N1 is passed to humans only from birds and is not transmissible between humans. But if it were to swap genes with another influenza virus, possibly H1N1 (through, for example, a patient who contracts the two illnesses simultaneously), a new, more lethal pandemic strain could emerge with a high rate of contagion. "I would say that is an unlikely scenario," Hay says. "But the point is you don't know what's going to happen. You have to remain alert...
What's clear is that childhood obesity cannot be solved in a single doctor's visit. Ludwig sometimes spends several sessions with a patient at his Boston clinic before coming up with a concrete plan - and persuading the child to cooperate. "Many children come in at first unwilling to talk about the problem. They feel so embarrassed," Ludwig says. But when change comes, it can make a huge difference. "With just the smallest tangible results, a sense of empowerment can grow," Ludwig says. "The child may go from denying a problem exists and fighting their parents' efforts tooth and nail...
...tree of life, we often envision evolution working like a patient gardener, pruning species that don't quite fit, bit by bit. But that's not how extinction works in practice. Throughout our planet's history, mass extinction has occurred five times - most recently 65 million years ago, when the dinosaurs finally died out - taking out vast amounts of life all at once, usually due to a catastrophic and sudden climatic change. (See pictures of the effects of global warming...