Word: patiently
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Dates: during 1980-1989
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...patient is on the table, dying but not yet dead," said a dejected Richard Gephardt, the Missouri Democrat who has made tax reform his major cause. But Reagan, who grew increasingly angry as he mulled over the G.O.P. defections, ordered his lieutenants to try to revive the moribund bill last week. Said Treasury Secretary James Baker as he headed off to Capitol Hill to cajole and arm-twist, "It ain't over till it's over...
...technique was tested on ten different types of cancer in 25 patients, for whom standard treatments had failed. Crucial to the experiment was a potent natural substance called interleukin-2 (IL-2), one of a variety of chemical messengers called lymphokines that help control the activities of the immune system. Studies have shown that IL-2 is capable of transforming certain white blood cells into powerful, anticancer killer cells. Using an elaborate blood-separating apparatus, Rosenberg and his team withdrew white cells from each patient and treated them with IL-2. After incubating for three or four days, the activated...
...results were impressive for several types of cancer. In eleven of the 25 patients, tumors shrank by 50% or more. Among the patients showing this response were three out of three with kidney cancer and four out of seven with melanoma, a particularly dangerous form of skin cancer that often spreads to the internal organs. In one melanoma patient who previously had widespread tumors, all signs of malignancy disappeared. There was, however, no response at all in 14 of the patients, and the outlook, even for those who have improved, remains uncertain; none has been observed for more than...
With further research, Rosenberg hopes to find a way around these difficulties and to make the technique less complicated and less costly. At present, the treatment calls for four to five weeks of hospitalization, a squadron of technicians for each patient and specialized lab facilities, all of which add up to a cost of tens of thousands of dollars for a single treatment. "Most hospitals would find it impossible to perform this procedure," he said. "There are a lot of problems to be worked...
...need a different combination," suggests Dr. Jordan Gutterman, of Houston's M.D. Anderson Hospital and Tumor Institute. IL-2 may also prove useful in combination with standard chemotherapy or as a follow-up to surgery. Stenzel theorized that after such traditional treatments, IL-2 could "gear up the patient's own cells to scavenge any remaining tumor cells...