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...seems logical that the most effective way to treat it is with biological agents. Secreted into the synapses, serotonin is normally partially reabsorbed by the brain cells that released it. SSRIs block this reabsorption, allowing more serotonin to accumulate in the synapses. The result, hopefully, is that the patient begins to feel better within a few weeks. But how solid is the chemical-imbalance model of depression? That depends on whom you ask. The drug companies present it as fact. On its website, Pfizer, maker of the blockbuster SSRI sertraline (Zoloft), asserts that antidepressants "work by correcting the chemical imbalance...

Author: /time Magazine | Title: Bitter Pills | 11/14/2005 | See Source »

...depression instead of the series of questions doctors use now. Don't hold your breath waiting for that, says British academic Moncrieff: "I believe that human emotions will never be located in a simple biochemical formula." The chemical-imbalance theory is nonsense, says Adelaide psychiatrist Jureidini. SSRIs alter a patient's serotonin levels within days, he says, but their antidepressant effect - if there is any - doesn't occur for several weeks. "The idea that there's a serotonin deficiency that explains depression is such a gross oversimplification as to be completely misleading," Jureidini says. "A lot of doctors and others...

Author: /time Magazine | Title: Bitter Pills | 11/14/2005 | See Source »

...walk," he says. "I've taken trips to Antigua and Florida. I feel like living life again." Grinstead owes his turnaround to TheraVitae, a two-year-old U.S.- and Israeli-run company that, in conjunction with local hospitals, offers treatment for heart disease with stem cells taken from the patient's own blood. (Bangkok was chosen as the firm's base because of its good medical facilities and relatively permissive policies governing medical procedures.) Using these cells carries several Loh and Behold Avant-garde murals and imaginative furnishings characterise a new Singapore hotel Identity Parade An iconic style magazine marks...

Author: /time Magazine | Title: Take Heart | 11/13/2005 | See Source »

Luckily for you, you can easily get back into The Game because­—whether we like it or not— the rules of romance are bendable. And be patient. As the shrewd Dolly Parton says, “if you want the rainbow, you must put up with the rain...

Author: By Nicole B. Urken, CRIMSON STAFF WRITER | Title: DEAR NIKKI: How To Get to Bed | 11/13/2005 | See Source »

...process is surprisingly simple. After arriving in Bangkok, the patient has about 250 cc of blood drawn?less than a standard blood donation. This is sent to the company's laboratory in Israel, where stem cells that occur naturally in the blood are isolated and multiplied through a patented process. A week later, a batch of several million stem cells is returned to Bangkok. These are inserted by surgeons into the patient's arteries or heart, using procedures that Patel helped to develop in the U.S. Patel says that when the cells are released into coronary arteries using an angioplasty...

Author: /time Magazine | Title: Take Heart | 11/12/2005 | See Source »

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