Word: patients
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Dates: during 1990-1999
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...genes in, change the cell's properties and do other things that ought to enable you to treat disease successfully." That is precisely what Anderson and his colleagues did eight years ago in the first approved use of gene therapy, when they removed blood cells from a young patient, genetically altered them with a viral vector and infused them back into her bloodstream...
...Because virtually the only cells that divide in the brain are tumor cells, the retroviruses infected them alone, inserting the herpes gene into their nuclei. As this gene expressed itself, it made the tumor cells sensitive to the herpes drug ganciclovir. When the drug was then administered to the patient, says Anderson, it "made the tumor cells commit suicide." But here there were troublesome side effects...
...heart-patient trial, St. Elizabeth's Isner found a novel way around the delivery problem. Eschewing virus carriers, he fashioned a construct called "naked DNA." It consists of part of a human gene called VEG-F, which stimulates the growth of blood vessels, and includes its signal segments. These segments, Isner explains, "order the cell, once it has manufactured the gene product, to export it from the cell...
...latest installment in Robin Williams' campaign for screen sainthood casts him as Hunter ("Patch") Adams, a medical student whose belief that "we have to treat the patient as well as the disease" sends him into patients' rooms with balloon animals, an enema-bulb clown nose and a song in his heart (Blue Skies...
...administering a lethal injection to a terminally ill patient [NATION, Dec. 7], Dr. Jack Kevorkian should be prosecuted to the fullest extent of the law. In his stubborn, egocentric wisdom, Kevorkian has become judge, jury and executioner. After I had open-heart surgery 10 years ago, I could hardly breathe and struggled desperately. A medical technician repeatedly came by to see me, and at one point, in fierce pain, I scribbled in pencil, "Kill me!" At long last I recovered my health. Before that incident my instinct for self-preservation had never wavered, nor has it since. All aspects...