Word: patients
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Dates: during 2000-2009
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...says Dr. David Sachs, a surgeon at Mass General and Harvard who led the study, is to prepare a patient's immune system well before the surgery?or, to be more exact, to deplete the immune system's T cells, which normally patrol the body looking for foreign invaders like bacteria, viruses and tissues from outside donors. Several days before the transplant surgery, Sachs' team used drugs that target and eliminate these cells to wipe the immune slate clean. Then the team transplanted the kidney along with donor bone-marrow cells. What happened next was surprising: the bone marrow rebuilt...
...retrains the immune system, fooling it into thinking that the donor tissue is now part of the self," says Sachs. One patient was able to stop taking antirejection drugs as early as nine months after his surgery?though not without some discomfort as the body adjusted. "There is no question that during the initial phase, the patient has a lot more difficult time. But they trade that difficulty with what is beginning to look like lifelong suppression [of rejection]," says Sachs...
...original version of this article mistakenly reported that surgeons transplanted a donated kidney along with bone-marrow cells that had been harvested from the patient. In fact, the bone-marrow cells also came from the donor...
...Fridays, the class will apply the week’s discussion on the specific metabolic pathway to real-life, bringing in a patient who is suffering from a disease related to that metabolic pathway. According to Michel, because of patient confidentiality issues, undergrads will have to travel to HMS for the Friday lectures...
...renders Kosovo’s statehood immaterial. The only way to look beyond this wedge is to look above it—to the continental level of the European Union (EU).The EU must take a leading role in defusing the dispute. First, it should urge Kosovo to be patient in declaring its independence. Then the EU should guide Serbia and Kosovo, still as one country, toward separate membership in the union. Eventually, Serbia will join the EU, Kosovo will join the EU, and Kosovo will be released from Serbian rule—all on the same day. Only thus...