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...Canada, though its maker has yet to seek approval in the U.S. But last week it completed its U.S. clinical study, and the results were impressive. Restylane outperformed a collagen-based substance by a 6-to-1 ratio. Unlike collagen, which lasts only about three months for some patients, Restylane can last six months or longer, doctors say. And because it's a non-animal-based gel created in the lab (bovine collagen is made from cow tissue), it doesn't cause allergic reactions, as collagen does in a few patients. That means no waiting six weeks for allergy-test...

Author: /time Magazine | Title: Beyond Botox: A Shot At Beauty Heaven | 5/20/2002 | See Source »

...overt, to downplay trial risks. I would definitely advise my family and friends not to enroll in a clinical trial. If you are taking part in a trial, you should be aware that your safety is often the last priority. And never forget that you are not a patient being treated; you are a subject in an experiment. NAME WITHHELD BY REQUEST Tampa...

Author: /time Magazine | Title: Letters: May 13, 2002 | 5/13/2002 | See Source »

Clinical researchers believe in their treatments, as they should. Yet this belief needs to be scrutinized by unbiased scientists working in the patients' interest. Our trials can never be too safe. But we should not lose sight of the fact that our system has given rise to spectacular advances in cancer therapy, including Gleevec for leukemia; the control of aids; treatments for breast cancer; and others. As a new era of molecular genetic research dawns, we need to make certain that the strides we make in devising new therapies are matched by progress in ensuring patient safety. FRANK G. HALUSKA...

Author: /time Magazine | Title: Letters: May 13, 2002 | 5/13/2002 | See Source »

...group that steps in when a drug causes death or severe side effects. Companies should be forced to provide information on the risk and all possible side effects to keep the participants as safe as possible. As long as profit is the main goal of the researchers, however, patient safety will be something of a pipe dream. TODD KITCHENS Emporia, Kans...

Author: /time Magazine | Title: Letters: May 13, 2002 | 5/13/2002 | See Source »

Health professionals need to be more alert to older patients' substance abuse, cautions a new report in the Elder Law Journal. As many as 1 in 6 Americans age 60 or older is overly dependent on alcohol; one-third of these heavy drinkers are "late-onset abusers" who turn to drink after a major lifestyle change, such as the death of a spouse. Many doctors fail to consider substance abuse as a cause of symptoms. Others shrug off suspicions because they feel the patient "does not have much else to look forward...

Author: /time Magazine | Title: Your Family: May 13, 2002 | 5/13/2002 | See Source »

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