Word: patients
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...Zhang can be patient because he seems to have the master reel already filmed and locked away in his head. "I don't start shooting until I know exactly how every scene will look," he says. And he's not exaggerating. He delights in the minutiae of his vision. The rhythm. The angles. His taciturn bearing vanishes as he pantomimes the way his camera will trace the edge of Jet Li's sword or follow a tear down Cheung's cheek. When Cheung complains that he makes her cry too often, he counters, "Nothing moves me more than the sight...
...Aaron Diamond AIDS Research Center in New York City, "because cell membranes can present barriers to some drugs, and some have molecules that pump out drugs that manage to get inside." This suggests that the new drugs might be effective at lower doses, making fusion inhibitors safer for the patient in the long run. Trimeris' studies support this; so far, neither of its compounds seems to cause any of the serious toxic side effects associated with today's AIDS drugs, such as nausea, vomiting and abnormalities in fat metabolism...
...researchers have positioned out of sight in a watery maze. There are now strong hints that retarding the development of plaques helps preserve intellectual performance, at least in rodents. And that raises an intriguing question: Might getting rid of plaques once they have developed do more than slow a patient's decline...
Many of the new therapies also happen to be incredibly potent. Last month, for example, pharmaceutical giant Novartis reported spectacular results in a clinical trial of Glivec, a drug that disables a uniquely aberrant protein produced inside cells of chronic myelogenous leukemia, which afflicts 4,400 new patients in the U.S. each year. In the drug's very first test, every patient went into remission. In the most recent results, 30% showed no sign of the chromosomal damage that marks the disease and appeared to have been cured. "This drug is amazing," says Richard Stone, an oncologist at the Dana...
...weak, he says, "I could not sneeze without holding on to something." His doctors put him on Dendreon's experimental treatment Mylovenge, which required extracting dendritic cells from Omidian's blood, mixing them with molecules from myeloma cells and then returning them to the patient so they could deliver a swift kick to his immune system. Within two weeks, Omidian felt strong enough to return to work. Within two months, his cancer was in a remission that lasted until late last year, when he resumed treatment with Mylovenge...