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...drugs through development in only two-thirds the time it takes the average drug company. Its tightly coordinated R.-and-D. and marketing efforts focus on areas, such as cardiovascular diseases, in which treatments are judged to offer the greatest potential for profit. Senior vice president for business development Paul Sekhri, who helped pick these areas by going systematically through some 980 categories of ailments, says Vasella took a keen interest in how they were chosen. But while Vasella has taken aim at larger markets, he has ensured that more specialized products, such as ophthalmologic drugs, are not neglected...

Author: /time Magazine | Title: Drug Lord | 11/13/2007 | See Source »

...signing an exploratory multiyear licensing deal with the $120 million company Palomar Medical Technologies to develop, test and commercialize light-based aesthetic devices that can treat wrinkles, cellulite and acne. "We have the potential to penetrate a good part of that market," says Palomar's chief financial officer, Paul Weiner--but so far no commercial product...

Author: /time Magazine | Title: Cosmetics: The Newest Wrinkle | 11/12/2007 | See Source »

...Christmas Eve, moviegoers had hopes for this one. Vince Vaughn and David Dobkin, the star and director of Wedding Crashers, reunite for a holiday comedy scripted by Dan Fogelman (one of the screenwriters of the Pixar movie Cars). Supporting Vaughn as the black sheep of the Claus clan and Paul Giamatti as Santa, the picture's got three Academy Award winners: Kathy Bates as their mother, Rachel Weisz as Fred's ill-used girlfriend and Kevin Spacey as a corporate type threatening to close down Santa's workshop. Giamatti and Miranda Richardson, who plays his wife, have been Oscar-nominated...

Author: /time Magazine | Title: The Claus That Won't Fly | 11/11/2007 | See Source »

...must have seemed like a good idea: take a familiar tale—the Santa Claus story—and breathe some life into it by means of talented actors. Cast box office king Vince Vaughn as the protagonist, throw in a little Paul Giamatti, Kathy Bates, and Rachel Weisz to add some Oscar cred, and get Kevin Spacey to play the villain. You’ve gotta get Spacey to play the villain. The man put Gwyneth Paltrow’s head in a box in “Se7en,” so he’s sure...

Author: By Ruben L. Davis, CRIMSON STAFF WRITER | Title: Fred Claus | 11/9/2007 | See Source »

Assistant Dean of the College Paul J. McLoughlin II wrote in an e-mailed statement that while tailgate regulations differ between the two schools, both share common goals and difficulties in hosting the event each year...

Author: By Aditi Balakrishna, CRIMSON STAFF WRITER | Title: Yale: Tailgate Will Be Dry | 11/9/2007 | See Source »

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