Word: penbritin
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...breakthrough came in 1959 with the isolation of 6-aminopenicillanic acid, which is the hard core of all penicillin molecules. The new Penbritin is the first modification found to be active against a wider range of bacteria...
...from being a single, simple drug, penicillin is a whole family of drugs with slightly differing properties that determine which one is best for a particular illness. Together they make up the royal family of antibiotics. Last week the British were saluting the arrival of a new penicillin prince, Penbritin,* which promises to carry the fight against groups of microbes that have defied all previous penicillins. If it fulfills its early promise, Penbritin will become the first-choice drug against several forms of food poisoning, certain types of respiratory infections and meningitis, and possibly typhoid fever as well...
...test tube, Penbritin has proved deadly to a variety of disease-causing microbes. Tried on a small number of British patients, it swiftly cleared up stubborn infections of the urinary tract, including some caused by the common colon bacteria, Escherichia coli. Test tube promise was not fulfilled in intestinal infections caused by one of the commonest forms of Salmonella; after a brief clearing, the microbes reappeared. More trials in many patients will be needed to show whether Penbritin can be useful against the several forms of Salmonella and Shigella that cause much dysentery and enteric fever, and, most importantly, against...
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