Word: penicillin
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...many varieties of penicillin have a unique disadvantage: about one in a hundred patients who get them by injection becomes sensitized, so that his next shot may produce a severe reaction marked by rash, fever, swollen glands and pain in the joints. In a few cases, the response is so fast and catastrophic that it is called anaphylactic shock, a violent reaction usually associated with the introduction of foreign protein into the system. A patient thus afflicted may die within minutes...
...Since penicillin molecules are not proteins, he reasoned, they must somehow get hooked up to a protein. Sure enough, when he had basic penicillin preparations put through careful laboratory separation procedures, two fractions appeared: a pure penicillin that did not cause reactions in sensitized guinea pigs and a minute quantity of a second substance that produced violent reactions. This second substance proved to be a large protein molecule, with part of the penicillin molecule attached. The protein can be removed in the final stages of manufacture, thus making injected penicillin much safer for the non-sensitized patient...
...Nobel Prize winners, Lord Florey for work on penicillin, and Fritz Lippman for his research on intermediate metabolism, received Doctor of Science Degrees...
...Howard Walter Florey, President of the Royal Society since 1960, shared the 1945 Nobel Prize with Chain of Germany and Fleming of England for the preparation of penicillin in concentrated form...
...identical chemicals, meeting the same U.S. Government standards of purity and potency, are available for less under their generic names. Drug by drug, Dr. Burack lists many of the most widely used medications, gives their brand names and lists the prices charged for them. For example, he cites penicillin G, sold by E. R. Squibb & Sons as Pentids at a price to the druggist of $6.62 per 100, but for 92? by Pennex Products Co., and by 15 other companies for less than $2. Or digitalis, sold as Pil-Digis by Davies, Rose-Hoyt...