Word: penicillins
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Crushed Legs. Like Sir Alexander Fleming's discovery of penicillin, the high blood pressure discovery was almost an accident. During London's 1941 air raids, doctors found that victims whose legs had been pinned under timbers or masonry for several hours sometimes died mysteriously of kidney failure. The puzzled doctors called this strange death "crush syndrome." To find out what a crushed leg had to do with the kidneys, Spanish-born Dr. Josep Trueta and four co-workers at Oxford's Nuffield Institute for Medical Research* began some blood-circulation experiments on rabbits...
...Dyer of the U.S. Public Health Service tags penicillin molecules with radioactive sulphur, then traces the drug through the human body to find out just where it goes and what eventually happens...
...been observed that anti-biotics (such as penicillin), produced by soil bacterial have molecular structures like proteins, although the overall size is considerably smaller. With Woodward's general method, many of these so-called antibiotics have been tured out, but their effectiveness is at yet untested...
When doctors first announced (in 1943) that penicillin would remove all signs of early syphilis in eight days, many a layman concluded that penicillin was a sure syphilis cure. But syphilologists, knowing the wily ways of the spirochete, were careful to use the word "cure" only in cautious quotation marks...
Johns Hopkins' Dr. Margaret Merrell went to work and rounded up the clinical records of 15,000 patients treated for early syphilis throughout the U.S. over a two-year period. Last week she announced her findings: 20 months after getting penicillin treatment, between 25% and 30% of the patients still had positive blood tests; How many cases were relapses, and how many reinfections? It was impossible to tell. The other 70-75% were apparently cured, i.e., they showed no clinical symptoms and had negative blood tests. But doctors still stuck to their cautious qualifications...